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TOPIC: The new Alzheimer's drug Aduhelm

The new Alzheimer's drug Aduhelm 2 months 1 week ago #3697422

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link will be posted soon...

sorry, I am unable to get the link to upload.
If anyone else want to give it a go, thank you.
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Last edit: by AntiqueLace1.

The new Alzheimer's drug Aduhelm 2 months 1 week ago #3697431

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www.alz.org/alzheimers-dementia/treatments/aducanumab

Aducanumab Approved for Treatment of Alzheimer’s Disease

Aducanumab (Aduhelm™) has received accelerated approval as a treatment for Alzheimer’s disease from the U.S. Food and Drug Administration (FDA). This is the first FDA-approved therapy to address the underlying biology of Alzheimer’s disease.

It is the first therapy to demonstrate that removing amyloid, one of the hallmarks of Alzheimer’s disease, from the brain is reasonably likely to reduce cognitive and functional decline in people living with early Alzheimer’s.

Approval of this therapy underscores the importance of early detection and accurate diagnosis. We encourage people who are interested in learning more about this treatment, for themselves or a loved one, to have a conversation with their health care provider.
Aducanumab FAQs
Is aducanumab a cure for Alzheimer’s and all other dementia?

No. Aducanumab is the first drug to address the underlying biology of the disease. According to the FDA, aducanumab reduces amyloid plaques, which is reasonably likely to lead to a reduction in clinical decline due to Alzheimer’s disease.

This could mean more time for individuals to actively participate in daily life, have sustained independence and hold on to memories longer.
Who should take this drug?

Aducanumab is indicated for the treatment of Alzheimer’s disease. Treatment with aducanumab should be initiated in patients with mild cognitive impairment (MCI) or mild dementia stage of disease, the population in which treatment was initiated in clinical trials.​

Aducanumab was studied in people living with early Alzheimer’s disease and MCI due to Alzheimer’s who showed evidence of a buildup of amyloid plaques in the brain. There is no safety or effectiveness data on initiating treatment at earlier or later stages of the disease than were studied.
Understanding aducanumab

Aducanumab could mean more time for individuals to actively participate in daily life, have sustained independence and hold on to memories longer. Our information guide can help you understand this new treatment.

Will this drug restore memories or cognitive function that has been lost?

There is no evidence that aducanumab can restore lost memories or cognitive function.
What type of diagnostic test is the FDA requiring?

The FDA is not requiring any specific diagnostic test. However, the label says aducanumab is indicated for the treatment of Alzheimer’s, based on reduction in amyloid beta plaques, one of the hallmarks of the disease. This means that a physician should confirm the presence of amyloid plaques in the brain before prescribing this anti-amyloid plaque treatment.

Confirmatory tests like cerebrospinal fluid analysis or amyloid PET imaging should be a part of the diagnostic process to determine eligibility for the treatment.
How do I receive this treatment?

If you or a loved one is experiencing memory changes, the Alzheimer’s Association strongly encourages speaking with a health care provider for a thorough evaluation and diagnosis. Aducanumab may be a treatment option.
How is this drug administered?

Aducanumab is administered intravenously (IV) via a 45- to 60-minute infusion every 4 weeks. Infusion can be done at hospitals or infusion therapy centers.
When will it be available at my doctor?

Now that aducanumab is approved, nationwide distribution and implementation will take some time.
What are the side effects?

What is mild cognitive impairment?

Mild cognitive impairment (MCI) is an early stage of memory loss or other cognitive ability loss in individuals who maintain the ability to independently perform most activities of daily living.
The most common side effects include amyloid-related imaging abnormalities (ARIA), headache and fall. Another potentially serious side effect is allergic reaction. ARIA is a common side effect that does not usually cause symptoms but can be serious. It is typically a temporary swelling in areas of the brain that usually resolves over time. Some people may also have small spots of bleeding in or on the surface of the brain with the swelling, although most people with swelling in areas of the brain do not have symptoms. Some may have symptoms of ARIA such as headache, dizziness, nausea, confusion and vision changes.

Can I take this drug with my other medications/supplements?

When considering any treatment, including aducanumab, it is important to have a conversation with your health care provider to ensure you are a candidate for the treatment. This includes taking into account other health conditions, medications or supplements.
How will COVID-19 impact my ability to get this treatment?

Throughout the pandemic, our health care systems have adapted. People have continued to receive treatments, including infusions such as chemotherapy, with extra precautions such as social distancing and wearing a mask. Talk to your doctor to find out if aducanumab is right for you or a loved one, and discuss a plan to identify extra precautions for COVID safety.
Alz Talks logoALZ Talks: New Advancements in Alzheimer’s Treatments

Our 30-minute webinar about aducanumab features Dr. Salloway and Dr. Edelmayer reviewing what the treatment is, how it is administered, what it was designed to do, who is eligible to receive it and steps for accessing it. The Alzheimer's Association also offers support and resources for more information.


VIDEO on webpage.......
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The new Alzheimer's drug Aduhelm 2 months 1 week ago #3697435

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thank you Keeper, for posting the link ;)
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Last edit: by Eira. Reason: removed quoted duplicate article

The new Alzheimer's drug Aduhelm 2 months 4 days ago #3698815

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How well will Biogen's Alzheimer's drug Aduhelm perform in the real world? This study is set to find out

www.google.com/url?sa=t&rct=j&q=&esrc=s&...Ft5XbqCpBdvY_0vZMeHq



Aduhelm: What to Know

www.google.com/url?sa=t&rct=j&q=&esrc=s&...b1ERfdLEirbkUMYyb7mL



Aducanumab clears out clumps of a protein in the brain called amyloid-β, which some researchers think is the root cause of Alzheimer's. This theory is known as the amyloid hypothesis. The FDA approved the drug on the basis of its ability to reduce the levels of these plaques in the brain.

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Last edit: by senile1.

The new Alzheimer's drug Aduhelm 2 months 2 days ago #3699942

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As with all drugs, there will be side-effects. The same question applies, 'are the side-effects worth the benefits of taking the drug?'

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The new Alzheimer's drug Aduhelm 2 months 1 day ago #3699974

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Elizabeth wrote: As with all drugs, there will be side-effects. The same question applies, 'are the side-effects worth the benefits of taking the drug?'


While all drugs can potentially have side effects, not everyone who takes them will experience any side effects at all.

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Happy to help.

The new Alzheimer's drug Aduhelm 1 month 3 weeks ago #3701724

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At $56,000 per person, per year....they are going to need to bring this price way down on this drug so that the average person/senior can anywhere near afford it even with Medicare.

It's very promising.

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The new Alzheimer's drug Aduhelm 1 week 3 days ago #3721667

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My mother has just been diagnosed with Alzheimers by the memory clinic and has just started taking medication this week but not sure of the name of it but I'm hoping it will help her!

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The new Alzheimer's drug Aduhelm 1 week 3 days ago #3721685

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Butterfly123 wrote: My mother has just been diagnosed with Alzheimers by the memory clinic and has just started taking medication this week but not sure of the name of it but I'm hoping it will help her!


I wish your mother and all concerned all the best and hope that the medication prescribed will help.
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